Next Session: Tuesday, November 24th 2020, 11:30 CET, 3pm IST, 5:30 CST This interactive session will include a full CASE Ultra demonstration using the OECD validated Bacterial Mutagenicity models intended for ICH M7 submissions. The demo will conclude with an open Q&A that will allow topic discussion along with continued technical input from MultiCASE scientific team. Every third Tuesday, September 2020 through November 2021
Computational Toxicology Research Associate MultiCASE is seeking a candidate for an open position of Computational Toxicology Research Associate to conduct (Q)SAR modeling research projects. This position requires special attention to cheminformatics, specifically in the pharmaceutical and computational toxicology area. Experience of programming in R, Python will be a plus. In addition, good scientific writing and communication skills will be required. Please send letter of interest and resume to : info@multicase.com
2020 Tentative Conference Schedule
Eurotox Copenhagen, Denmark - Cancelled September 6th-9th Genotoxic Impurities VIRTUAL September 15th-16th FDA Scientific Computing Day VIRTUAL September 29th-30th Event Website American Society for Cellular and Computational Toxicology (ASCCT) VIRTUAL October 20th-23rd Event Website American College of Toxicology (ACT) VIRTUAL November 15th-18th Exhibitor Hosted Program Friday November 13th, 3:00-3:55 pm Reducing the Gap between QSAR and Expert Review Outcomes Event Website
Session 1- June 9th, 2020, 3:00-4:00 PM IST Applying Expert Knowledge in ICH M7 Impurity Classification This session will outline the principles of (Q)SAR safety evaluations for the assessment of the mutagenic potential of impurities. https://www.youtube.com/watch?v=YeZUNjaZ0t8&t=1145s Session 2- July 7th, 2020 3:00-4:00 PM IST Focused ICH M7 (Q)SAR Analysis with Case Studies Follow along through expert review of results from statistical and expert rule-based (Q)SAR models during ICH M7 safety assessments. Including presentations from Gilead Sciences and Pharmalex. https://www.youtube.com/watch?v=3aEakG1JVL0&t=267s Session 3- August 4th, 2020 3:00-4:00 PM IST ICH M7 Expert Review: Advanced Concepts and Applications In-depth analysis for complicated or conflicting results with industry presentations from Amgen and Dr Reddy's Labs https://www.youtube.com/watch?v=mpNwq70VkCo&t=306s
News
Dr. Roustem Saiakhov presents New QSAR model for Inhalation Toxicity
We are pleased to present the latest developments in our Inhalation Toxicity Models while continuing partnership with PETA International Science Consortium (PISC). Please visit PISC website to view other webinars.
< News Archive >
*** August 16, 2016: We are very happy to announce that the Research Collaborative Agreement (RCA) between MultiCASE Inc and US FDA's Center for Drug Evaluation and Research (CDER) has been extended for another 5 years till July 2021. The title of the RCA project is Enhancement of In Silico Decision Support Tools for the Evaluation of Drug Safety. We are looking forward for a lot of productive research and exciting innovations with CDER in this duration.
MultiCASE attended the 17th International Conference on QSAR in Environmental and Health Sciences, June 13–17, 2016, Miami, FL, USA.
MultiCASE attended the Society of Toxicology 55th Annual Meeting and ToxExpo, March 13–17, 2016. Poster:CASE Ultra Konsolidator: A Knowledge Driven Algorithm to Assist in Expert Review of ICH M7 Based (Q)SAR Analysis of Bacterial Mutagenicity of Impurities.
10/6/2015: MultiCASE attended Annual Meeting of American College of Toxicology November 8-11, 2015, Red Rock Resort, Summerlin, Nevada, US.
10/7/2015: MultiCASE Users' Meeting in Japan took place on October 6, 2015 in Tokyo.
10/5/2015: MultiCASE attended 3rd Annual FDA Scientific Computing Day, Washington DC, USA, September 9, 2015.
3/23/2015: MultiCASE hosted an exhibitor session “In Silico approach to the ICH M7 challenges” and several poster presentations (abstracts #1313, #2210, and #2211) at SOT 2015 Annual Meeting in San Diego.
1/23/2015: We released a fully featured Expert Rule based system for mutagenicity prediction in addition to new statistical models for E. coli and Salmonella mutagenicity.
11/28/2014: MultiCASE was a Gold Sponsor in the Elemental and Genotoxic Impurities Conference held at Hyatt Regency, Mumbai, India, 26-28 November 2014. We gave a platform talk on Alert Based QSARs.
9/19/2014: MultiCASE attended the American College of Toxicology’s 35th Annual Meeting from November 9–12, 2014, at the Hyatt Regency Grand Cypress in Orlando, Florida. It was a great experience in terms of meeting with great people and sharing and learning about progress being made at the frontier of toxicology research.
9/18/2014: MultiCASE attended the 2nd Annual FDA Scientific Computing Day at the FDA White Oak Campus in Silver Spring, Maryland.
7/22/2014: MultiCASE attended the Eurotox Meeting at Edinburgh, from 7th to 10th September 2014. We presented a poster titled “An improved workflow to perform in silico mutagenicity assessment of impurities as per ICH M7 guideline”.
5/6/2015: MultiCASE attended GTA 2015 Annual Meeting in Newark, Delaware.
10/5/2015: MultiCASE attended 51st Annual Congress of the European Societies of Toxicology, Porto, Portugal, September 13-16, 2015, had an Exhibitor Booth and poster presentation.
