ICH M7

Pharmaceutical Impurities

Carcinogenic Potency

Nitrosamine Evaluation

Drug Discovery

Early Stage De-Risking

Modeled Endpoints

MultiCASE (Q)SAR models are fit for purpose and validated according to OECD principles

Bacterial Mutagenicity/ICH M7 more

Genotoxicity

Carcinogenicity

Skin Sensitization

Acute Toxicity

Endocrine Disruption

Reproductive Toxicity

Developmental Toxicity

Cardiotoxicity

Hepatotoxicity

Renal Toxicity

ADME

Ecotoxicity

Carcinogenic Potency of N-Nitrosamines more

Molecular Properties

Ecotoxicity

Human Metabolite Formation

Metabolite Reactivity Screen more